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Herbs for Libido: Which Have Any Human Evidence?
None of the common libido herbs has strong human proof. Maca has a few small trials, ashwagandha and muira puama have limited or low-quality data, and horny goat weed and catuaba rest mostly on rat and lab work. Tribulus was ineffective for testosterone in a review. Natural does not mean safe or proven.
Written by the Stallion Power label deskUpdated · 5 min read

Which herbs for libido have human evidence?
A few have small human trials. Most have little more than animal work. None has the large, well-run trials that would settle the question.
The table ranks six libido herbs found on the Stallion Power label from most to least human evidence, using only the sources we read. A higher rank means more human data, not proof that it works.
| Rank | Herb | What the sources say |
|---|---|---|
| 1 | Maca | A few small human trials; limited evidence for sexual function (MSK, Maca) (Shin 2010, Maca systematic review) |
| 2 | Ashwagandha | Limited human data; sources do not say it improves erections (MSK, Ashwagandha) (NCCIH, Ashwagandha) |
| 3 | Muira puama | Small, low-quality human data; robust trials are lacking (Drugs.com, Muira puama) |
| 4 | Tribulus | Review of 11 studies: ineffective for increasing testosterone; ED data mixed (MSK, Tribulus terrestris) (Qureshi 2014, Tribulus review) |
| 5 | Horny goat weed | Clinical data lacking; support is from rat and lab studies (Drugs.com, Horny goat weed) |
| 6 | Catuaba | Mostly lab and animal work; no human sexual-function trial found (Catuaba, Trichilia catigua review) |
What stands behind the top and bottom of the list?
Maca leads because it has any trials at all. A systematic review found four randomized trials, with two positive, one null and one in men with erectile dysfunction showing a score change. The authors still called the evidence limited (Shin 2010, Maca systematic review).
Muira puama comes next. Drugs.com says robust clinical studies are lacking (Drugs.com, Muira puama). One study of 262 men used 1,000 to 1,500 mg of extract a day for two weeks, as described there (Drugs.com, Muira puama).
At the bottom, horny goat weed and catuaba show mostly lab and animal results. The only catuaba human study described in the review tested a multi-plant product for burning mouth syndrome, not sexual function (Catuaba, Trichilia catigua review).
A rat study can show a pathway. It cannot tell you what a capsule does in a man. The FTC says animal and lab studies are not enough on their own to support a health claim (FTC, Health Products Compliance Guidance).
Is testosterone booster natural, and does natural mean safe?
When people ask if a testosterone booster is natural, or look for a testosterone booster natural option, they usually mean plant-based. Many are. But natural is a description of origin, not a safety rating. NIH says natural does not always mean safe, and gives kava and liver disease as an example (NCCIH, Using Dietary Supplements Wisely).
- Ashwagandha has been linked to rare liver injury (NIH LiverTox, Ashwagandha).
- Horny goat weed has case reports of heart rhythm problems, and MSK says not to take it with heart disease (MSK, Epimedium (horny goat weed)).
- Tribulus has reports of kidney problems and priapism (MSK, Tribulus terrestris).
- Green tea extract, also on this label, is linked to acute liver injury at high extract doses (NIH LiverTox, Green tea extract).
The FTC adds that a botanical called natural may still carry interaction risks that should be disclosed (FTC, Health Products Compliance Guidance).

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The label puts muira puama first, maca second and catuaba third in an 82 mg blend. Under the descending-order rule (21 CFR 101.36, Supplement Facts), the first place can hold at most 82 mg and the sixth place at most 5 mg. The tighter ceilings are 62, 33.5 and 24 mg for the first three. They are arithmetic, not lab results, and a real gummy can hold less. Two of those top three, muira puama and catuaba, have some of the thinnest human data on our list. See the ingredients page and supplement facts for every ceiling.
If you take nitrates or any medicine, have heart or liver disease, or are pregnant or nursing, ask before any herb. Keep taking prescribed medicine.
Next step: pick one herb from the table, read its page, and compare the amount a product prints to the amount studied. More background is in the guides hub.
Who wrote this01
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Pages built from the label, the sales page and linked NIH, FDA, FTC, NIDDK, AHA and peer-reviewed sources.
Last updated . See our editorial standards and how we check reviews. This website is run by Gostallionpower, a Stallion Power U.S. merchant desk, not by the manufacturer or the distributor named on the label. We earn money when you buy through our order links.
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